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protein immunohistochemistry ihc profiling data  (Human Protein Atlas)

 
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    Human Protein Atlas protein immunohistochemistry ihc profiling data
    Protein Immunohistochemistry Ihc Profiling Data, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/immunohistochemical+protein+data/ihc+immunohistochemistry/pm41686380-255-0-15
    Average 86 stars, based on 1 article reviews
    protein immunohistochemistry ihc profiling data - by Bioz Stars, 2026-09
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    Immunohistochemical staining:

    Article Title: A SNAI2-PEAK1 stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting a cytokine expression profile that converges on PI3K/Akt signaling
    Article Snippet: .. Immunohistochemical protein data from patient breast tumors are available in the Human Protein Atlas ( http://www.proteinatlas.org ). ..



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    protein immunohistochemistry ihc profiling data  (Human Protein Atlas)
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    DEGs of PD, NAFLD, and T2DM-related datasets.
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    immunohistochemical staining data of stat3 protein  (Human Protein Atlas)
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    Human Protein Atlas immunohistochemical staining data of stat3 protein
    Prognostic survival analysis. (a)−(c) K−M survival analysis showed that the OS of LGG, TGCT, and SKCM in <t>STAT3</t> high expression group was significantly different. (d) COX regression analysis showed that the OS of LGG and SKCM were significantly correlated with the expression of STAT3. (e)−(i) PFS of LGG, HNSC, SKCM, PRAD, and COAD were significantly different. (j) COX regression analysis showed that only LGG had significant difference in PFS and STAT3 expression.
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    Image Search Results


    (A) Illustrations of normal and KIRC tissues stained with immunohistochemistry. (B) The IHC scores of ALDOB in KIRC and normal tissues. (C) The IHC scores of ALDOB in pathologic stage I/II and II/III tissues (The pathologic stage is determined according to the 2016 WHO/ISUP grading classification). (D) The IHC scores of ALDOB in pathologic T1 stage and T2 stage tissues. (E) The IHC scores of ALDOB in AJCC stage II and AJCC stage I tissues.

    Journal: PeerJ

    Article Title: ALDOB is a prognostic biomarker and a potential immunotherapy target for clear cell renal cell carcinoma

    doi: 10.7717/peerj.19869

    Figure Lengend Snippet: (A) Illustrations of normal and KIRC tissues stained with immunohistochemistry. (B) The IHC scores of ALDOB in KIRC and normal tissues. (C) The IHC scores of ALDOB in pathologic stage I/II and II/III tissues (The pathologic stage is determined according to the 2016 WHO/ISUP grading classification). (D) The IHC scores of ALDOB in pathologic T1 stage and T2 stage tissues. (E) The IHC scores of ALDOB in AJCC stage II and AJCC stage I tissues.

    Article Snippet: Additionally, protein immunohistochemistry (IHC) data are available for tumors and normal tissues through the Human Protein Atlas (HPA).

    Techniques: Staining, Immunohistochemistry

    DEGs of PD, NAFLD, and T2DM-related datasets.

    Journal: Heliyon

    Article Title: Identifying MS4A6A + macrophages as potential contributors to the pathogenesis of nonalcoholic fatty liver disease, periodontitis, and type 2 diabetes mellitus

    doi: 10.1016/j.heliyon.2024.e29340

    Figure Lengend Snippet: DEGs of PD, NAFLD, and T2DM-related datasets.

    Article Snippet: The immunohistochemical slices data of the MS4A6A protein in multiple organs were obtained from the human protein atlas (HPA) database ( https://www.proteinatlas.org/ ).

    Techniques:

    Validation of the efficacy of 4 hub feature genes (A) The ROC curves showing the diagnostic efficacy of these 4 genes in GSE164760, GSE10334, and GSE76895 datasets. (B) The ROC curves and violin plots showing the diagnostic efficacy and the expression level of the hub feature genes in GSE63067, GSE16134, and GSE76894 datasets, except for the CYTIP gene that is not matched in the GSE76894 validation dataset. (C) The correlations between the expression level of the MS4A6A gene and disease severity markers of PD, NAFLD, and T2DM. (CXCL8 for PD; NAS score for NAFLD; fasting glucose level for T2DM). PD, periodontitis; NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes.

    Journal: Heliyon

    Article Title: Identifying MS4A6A + macrophages as potential contributors to the pathogenesis of nonalcoholic fatty liver disease, periodontitis, and type 2 diabetes mellitus

    doi: 10.1016/j.heliyon.2024.e29340

    Figure Lengend Snippet: Validation of the efficacy of 4 hub feature genes (A) The ROC curves showing the diagnostic efficacy of these 4 genes in GSE164760, GSE10334, and GSE76895 datasets. (B) The ROC curves and violin plots showing the diagnostic efficacy and the expression level of the hub feature genes in GSE63067, GSE16134, and GSE76894 datasets, except for the CYTIP gene that is not matched in the GSE76894 validation dataset. (C) The correlations between the expression level of the MS4A6A gene and disease severity markers of PD, NAFLD, and T2DM. (CXCL8 for PD; NAS score for NAFLD; fasting glucose level for T2DM). PD, periodontitis; NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes.

    Article Snippet: The immunohistochemical slices data of the MS4A6A protein in multiple organs were obtained from the human protein atlas (HPA) database ( https://www.proteinatlas.org/ ).

    Techniques: Biomarker Discovery, Diagnostic Assay, Expressing

    Single-cell analysis and immunohistochemical staining data (A) Immunohistochemical staining graphs of the MS4A6A gene in various tissues. The graphs were acquired from the HPA database ( https://www.proteinatlas.org/ ). Red arrows below indicate the expression site and level of the MS4A6A gene. (B) The single-cell RNA sequencing analysis showing cell types expressing the MS4A6A gene in PD, NAFLD, and T2DM. The results suggested a high and unique expression of the MS4A6A gene in macrophages. The orange color refers to its expression level and the darker the orange color is, the higher expression level of the MS4A6A gene. NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes mellitus; PD, periodontitis.

    Journal: Heliyon

    Article Title: Identifying MS4A6A + macrophages as potential contributors to the pathogenesis of nonalcoholic fatty liver disease, periodontitis, and type 2 diabetes mellitus

    doi: 10.1016/j.heliyon.2024.e29340

    Figure Lengend Snippet: Single-cell analysis and immunohistochemical staining data (A) Immunohistochemical staining graphs of the MS4A6A gene in various tissues. The graphs were acquired from the HPA database ( https://www.proteinatlas.org/ ). Red arrows below indicate the expression site and level of the MS4A6A gene. (B) The single-cell RNA sequencing analysis showing cell types expressing the MS4A6A gene in PD, NAFLD, and T2DM. The results suggested a high and unique expression of the MS4A6A gene in macrophages. The orange color refers to its expression level and the darker the orange color is, the higher expression level of the MS4A6A gene. NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes mellitus; PD, periodontitis.

    Article Snippet: The immunohistochemical slices data of the MS4A6A protein in multiple organs were obtained from the human protein atlas (HPA) database ( https://www.proteinatlas.org/ ).

    Techniques: Single-cell Analysis, Immunohistochemical staining, Staining, Expressing, RNA Sequencing

    Intermolecular docking simulation results Intermolecular docking simulation results of the predicted drugs with MS4A6A protein.

    Journal: Heliyon

    Article Title: Identifying MS4A6A + macrophages as potential contributors to the pathogenesis of nonalcoholic fatty liver disease, periodontitis, and type 2 diabetes mellitus

    doi: 10.1016/j.heliyon.2024.e29340

    Figure Lengend Snippet: Intermolecular docking simulation results Intermolecular docking simulation results of the predicted drugs with MS4A6A protein.

    Article Snippet: The immunohistochemical slices data of the MS4A6A protein in multiple organs were obtained from the human protein atlas (HPA) database ( https://www.proteinatlas.org/ ).

    Techniques:

    Prognostic survival analysis. (a)−(c) K−M survival analysis showed that the OS of LGG, TGCT, and SKCM in STAT3 high expression group was significantly different. (d) COX regression analysis showed that the OS of LGG and SKCM were significantly correlated with the expression of STAT3. (e)−(i) PFS of LGG, HNSC, SKCM, PRAD, and COAD were significantly different. (j) COX regression analysis showed that only LGG had significant difference in PFS and STAT3 expression.

    Journal: Open Medicine

    Article Title: A pan-cancer analysis of STAT3 expression and genetic alterations in human tumors

    doi: 10.1515/med-2023-0792

    Figure Lengend Snippet: Prognostic survival analysis. (a)−(c) K−M survival analysis showed that the OS of LGG, TGCT, and SKCM in STAT3 high expression group was significantly different. (d) COX regression analysis showed that the OS of LGG and SKCM were significantly correlated with the expression of STAT3. (e)−(i) PFS of LGG, HNSC, SKCM, PRAD, and COAD were significantly different. (j) COX regression analysis showed that only LGG had significant difference in PFS and STAT3 expression.

    Article Snippet: The immunohistochemical staining data of STAT3 protein in normal and glioma tissues were obtained from the Human Protein Atlas (HPA, https://www.proteinatlas.org/ ).

    Techniques: Expressing

    Verification of CGGA: (a) result of K−M survival analysis, (b) results of univariate analysis, (c) results of multivariate analysis, (d) ROC curve, (e) immunohistochemical staining showed that STAT3 was negative staining in normal tissue, and (f) immunohistochemical staining showed that STAT3 was medium positive in LGG.

    Journal: Open Medicine

    Article Title: A pan-cancer analysis of STAT3 expression and genetic alterations in human tumors

    doi: 10.1515/med-2023-0792

    Figure Lengend Snippet: Verification of CGGA: (a) result of K−M survival analysis, (b) results of univariate analysis, (c) results of multivariate analysis, (d) ROC curve, (e) immunohistochemical staining showed that STAT3 was negative staining in normal tissue, and (f) immunohistochemical staining showed that STAT3 was medium positive in LGG.

    Article Snippet: The immunohistochemical staining data of STAT3 protein in normal and glioma tissues were obtained from the Human Protein Atlas (HPA, https://www.proteinatlas.org/ ).

    Techniques: Immunohistochemical staining, Staining, Negative Staining

    Results of immune correlation analysis: (a) immune score of LGG by IME analysis, (b) matrix score of LGG by IME analysis, (c)−(k) results of immune cell infiltration, and (l) correlations between immune checkpoints and STAT3 expression.

    Journal: Open Medicine

    Article Title: A pan-cancer analysis of STAT3 expression and genetic alterations in human tumors

    doi: 10.1515/med-2023-0792

    Figure Lengend Snippet: Results of immune correlation analysis: (a) immune score of LGG by IME analysis, (b) matrix score of LGG by IME analysis, (c)−(k) results of immune cell infiltration, and (l) correlations between immune checkpoints and STAT3 expression.

    Article Snippet: The immunohistochemical staining data of STAT3 protein in normal and glioma tissues were obtained from the Human Protein Atlas (HPA, https://www.proteinatlas.org/ ).

    Techniques: Expressing

    Genetic alteration analysis: (a) radar map shows the correlation between STAT3 expression and TMB, (b) radar map shows the correlation between STAT3 expression and MSI, (c) alteration frequency of ADAM12 in different tumors, (d) mutation lollipop chart provides information on the mutation sites and mutation types, (e) 3D structure of the STAT3 protein and the Y640F site, (f) an overview of the types of mutations observed that are curated by COSMIC, (g) protein sequence features of STAT3 protein curated by COSMIC, and (h) 3D structure and missense mutation frequency of STAT3 protein that are curated by COSMIC (the redder the color, the higher the missense mutation frequency).

    Journal: Open Medicine

    Article Title: A pan-cancer analysis of STAT3 expression and genetic alterations in human tumors

    doi: 10.1515/med-2023-0792

    Figure Lengend Snippet: Genetic alteration analysis: (a) radar map shows the correlation between STAT3 expression and TMB, (b) radar map shows the correlation between STAT3 expression and MSI, (c) alteration frequency of ADAM12 in different tumors, (d) mutation lollipop chart provides information on the mutation sites and mutation types, (e) 3D structure of the STAT3 protein and the Y640F site, (f) an overview of the types of mutations observed that are curated by COSMIC, (g) protein sequence features of STAT3 protein curated by COSMIC, and (h) 3D structure and missense mutation frequency of STAT3 protein that are curated by COSMIC (the redder the color, the higher the missense mutation frequency).

    Article Snippet: The immunohistochemical staining data of STAT3 protein in normal and glioma tissues were obtained from the Human Protein Atlas (HPA, https://www.proteinatlas.org/ ).

    Techniques: Expressing, Mutagenesis, Sequencing